It is fast and amazingly accurate- errors occurring in only about one of a billion nucleotides. STUDY. Before DNA structure was discovered, all society knew about DNA was that DNA was most likely the main molecule of life and that it consisted of four. nucleus. DNA Replication Prior to cell division DNA has to make a copy of itself= DNA Replication Follows a template mechanism for this process much like a photograph is made from a photo negative. It was also important to figure out that the two strands run in opposite directions and that the molecule had a specific base pairing. %PDF-1.6 %���� V�b��x�"�����Q"���:��X�(��,�����V�GwjN�̫��5�uf��4;c�}g��۳��A�z;�sYl��%��l�9'����C�u`��eE|�\ rswH�:�K��y$��[=9LR�/��P\�L�����Qt�?���d_��p,���. Course Hero is not sponsored or endorsed by any college or university. Create your own unique website with customizable templates. Putting the Pieces Together: Before DNA structure was discovered, all society knew about DNA was that DNA was most likely the main molecule of life and that it consisted of four different kinds of bases (A, G, T, and C). h�25T0P05R0�T����+�-�� �b��B��.vv �U� endstream endobj 976 0 obj <>stream Erwin Chargaff was one of a handful of scientists who expanded on Levene's work by uncovering additional details of the structure of DNA, thus further paving the way for Watson and Crick. Case study Putting the Pieces Together The Discovery of DNA Structure and, 1 out of 2 people found this document helpful, Case study: “Putting the Pieces Together: The Discovery of DNA, Written responses to case study will be collected next class (finish, Quiz on chapter 12 & lecture 11 – 15 minutes, Before class: watch YouTube lecture 12, read chapter 13, Quiz on chapter 13 & lecture 12 – 15 minutes, Before class: watch YouTube lecture 13, read chapter 15, Review of DNA replication, Transcription, and Translation, Quiz on chapter 15 & lecture 13 – 15 minutes, Before class: watch YouTube lecture 14, read chapter 16, Group preparation of final draft of paper, figures, and figure, Formatted group paper and figures with legends MUST be, emailed to me as a Microsoft Word or PDF document by, Quiz on chapter 16 & lecture 14 – 15 minutes, Before class: watch YouTube lecture 15, read chapter 17, &, Making of the Fittest: Evolution of the Stickleback Fish — HHMI, Case study: “Modelling the Regulatory Switches of the PITX1, Written responses to case study will be collected next class, Discussions of poster with instructor and LAs, Quiz on chapter 17 & lecture 15 – 15 minutes, FINAL POSTER MUST BE PRINTED BY CLASS TIME TODAY, Extra credit for presenters (up to 8 points on final grade), Extra credit to attendees/reviewers (up to 2 points on final, Grades will be based on attendance, classwork, performance on. In order to solve the elusive structure of DNA, a couple of distinct pieces of information needed to be put together. In the 1890's and 1900's, scientists determined that the hereditary material was located in _____ protein, DNA. DNA has 3 main parts that make up each nucleotide; a phosphate group, a deoxyribose sugar, and a nitrogenous base. Discovery of DNA, Structure, and Replication. PLAY. This happens due to the way the bases bond. Chargaff, Watson and Crick, and Wilkins and Franklin. DNA was discovered in 1868 by a Swedish scientist. Each group will present on their chosen molecular. If you're seeing this message, it means we're having trouble loading external resources on our website. A and T pair together and are bonded by 2 hydrogen bonds, G and C pair together and are bonded by 3 hydrogen bonds, A and G are purines, which means they are double ringed, T and C are permidines, which means they are single ringed. 974 0 obj <>stream Genetics PCB 3063 syllabus Spring 18 (1).pdf, Florida International University • PCB 3063. Chargaff, Watson and Crick, and Wilkins and Franklin. The strands that make up DNA structure run "anti-parallel" to each other. One was that the phosphate backbone was on the outside with bases on the inside; another that the molecule was a double helix. With only this knowledge to go off of, many people believed that DNA was to “simple” to be the macromolecule of life. They are mirror images. )�I0 1�P1CK0ed��@T�~HeA�~@bzj��@� �� endstream endobj 975 0 obj <>stream This preview shows page 5 - 8 out of 11 pages. Putting the Pieces Together: The Discovery of DNA Structure and Replication Part I – Setting the Stage In the autumn of 1952, while the weather in London, England, was cooling down, the race to discover the structure of DNA was heating up inside two rival laboratories: the Cavendish Lab at Cambridge University and the laboratory of J.T. The structure of DNA double helix and how it was discovered. More than a dozen enzymes are involved in the process. He did not know what it did, what it looked like, or even its purpose, but he discovered it inside a cell's _____ chromosomes. P?$�e�q�)� �8�K�C��)B��|�� ob/��ޯ���&���A�J!`V"q��?C%���fL��MT�}�[�DO}}�*v!�%T�~�R���$_�L%E�P�*�� 0:05 Skip to 0 minutes and 5 seconds We began by introducing you to forensic science through the medium of a case study, and we will end it by reviewing how each chapter showed how science contributed to the development of the investigation. The case study - review. hޜ��n�8������AIT%:���;�Tr��vo�����~���"��J) (�~H���K\`�> -B='�1��lzĦ6#wpE^��0����D��*�9R> L5&��޿��k��i%��P�����b�,��B��F�NWda揎�^U��`�^]��Ws�+�"^��d�R�D+^N�zU�����po.z��dWj� Case study: “Putting the Pieces Together: The Discovery of DNA Structure and Replication” • Written responses to case study will be collected next class (finish at home if necessary) • Quiz on chapter 12 & lecture 11 – 15 minutes 12 Mar 28 Transcription • Before … ���Jij4kP�@+�CS�P>-(ud��>�#\@!�D�0�s�`��B��c�< Original strand Replicated strand 1 Replicated strand 2 h�25V0P���w�/�+Q����L)�65 exams and quizzes as well as the completion of the group project as follows: You can choose to drop Exam I or II, if you do this the final, exam will be worth 35% of the final grade, Case studies, Quizzes, & Attendance: 25% of final grade, Extra Credit: Earn up to 10 points on final grade, The group project consists of several parts all leading up to a poster presentation, at the end of the semester.

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